Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.50 |
| ▸ | MEN1 | O00255 | 7/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | GFER | P55789 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8593844 | 0.92 | TSHR (0.46) | KMT2AMEN1CYP2C9CYP1A2TSHR | |
| SCHEMBL8464230 | 0.90 | KMT2A (0.53) | KMT2AMEN1CYP2C9CYP1A2TSHR | |
| SCHEMBL27367262 | 0.86 | TSHR (0.49) | KMT2AMEN1CYP2C9CYP1A2TSHR | |
| SCHEMBL9766076 | 0.86 | TSHR (0.52) | KMT2AMEN1CYP2C9CYP1A2TSHR | |
| SCHEMBL8652422 | 0.86 | TSHR (0.47) | KMT2AMEN1CYP2C9CYP1A2TSHR | |
| SCHEMBL4247568 | 0.84 | KMT2A (0.51) | KMT2AMEN1CYP2C9CYP1A2TSHR | |
| SCHEMBL5702932 | 0.84 | MEN1 (0.54) | KMT2AMEN1CYP2C9CYP1A2TSHR | |
| SCHEMBL9766080 | 0.82 | TSHR (0.44) | KMT2AMEN1CYP2C9CYP1A2TSHR | |
| SCHEMBL28783675 | 0.82 | KMT2A (0.48) | KMT2AMEN1CYP2C9CYP1A2TSHR | |
| SCHEMBL29154296 | 0.82 | MEN1 (0.53) | KMT2AMEN1CYP2C9CYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010056633-A2 | 7-AMINO ALKYLIDENYL-HETEROCYCLIC QUINOLONES AND NAPHTHYRIDONES | JANSSEN PHARMACEUTICA NV (BE) | 2010-05-20 | — | — | WO | disclosed |
| US-20090156577-A1 | 7-AMINO ALKYLIDENYL-HETEROCYCLIC QUINOLONES AND NAPHTHYRIDONES | JANSSEN PHARMACEUTICA NV (BE) | 2009-06-18 | — | — | US | disclosed |
| US-20090156577-A1 | 7-AMINO ALKYLIDENYL-HETEROCYCLIC QUINOLONES AND NAPHTHYRIDONES | JANSSEN PHARMACEUTICA NV (BE) | 2009-06-18 | — | — | US | disclosed |
| EP-0877011-A1 | Processes for producing tetra-fluorophthalic anhydride and fluorobenzoic acids | ASAHI GLASS COMPANY LTD. (JP) | 1998-11-11 | — | — | EP | disclosed |
| EP-0866050-A1 | Processes for producing tetra-fluorophthalic anhydride and fluorobenzioc acids | ASAHI GLASS COMPANY LTD. (JP) | 1998-09-23 | — | — | EP | disclosed |
| US-5648504-A | MULTISTAGE PROCESS WITH CHLORINATION OF TETRACHLOROPHTHALIC ANHYDRIDE TO 3,3,4,5,6,7-HEXACHLORO-1-(3H)-ISOBENZOFURANONE THEN FLUORINATION AND REACTING WITH INORGANIC BASE OR ACID | ASAHI GLASS COMPANY LTD. (JP) | 1997-07-15 | — | — | US | disclosed |
| US-5523476-A | Processes for producing tetrafluorophthalic anhydride and fluorobenzoic acids | ASAHI GLASS COMPANY LTD. (JP) | 1996-06-04 | — | — | US | disclosed |
| EP-0669310-A1 | Processes for producing tetrafluorophtahlic anhydride and fluorobenzoic acids | ASAHI GLASS COMPANY LTD. (JP) | 1995-08-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156577-A1 | 7-AMINO ALKYLIDENYL-HETEROCYCLIC QUINOLONES AND NAPHTHYRIDONES | NQO2, QRFPR, NQO1 | KMT2A 1652/4885MEN1 1904/4885CYP2C9 174/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.