Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 3/20 | 0.34 |
| ▸ | CCKBR | P32239 | 6/20 | 0.33 |
| ▸ | WDR5 | P61964 | 2/20 | 0.33 |
| ▸ | ACLY | P53396 | 1/20 | 0.33 |
| ▸ | CCR9 | P51686 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7550772 | 0.84 | DHODH (0.38) | ALDH1A1KDM4EMAPTHPGDDHODH | |
| SCHEMBL7575613 | 0.80 | DHODH (0.33) | DHODHPOLBMAPK1 | |
| SCHEMBL6054844 | 0.79 | DHODH (0.35) | ALDH1A1HPGDDHODHWDR5CCR9 | |
| SCHEMBL6054845 | 0.78 | DHODH (0.33) | DHODHPOLBMAPK1 | |
| SCHEMBL8492072 | 0.78 | DHODH (0.38) | MAPTHPGDDHODHPOLB | |
| SCHEMBL8747845 | 0.77 | FLT1 (0.36) | ALDH1A1MAPTHPGDDHODHCCR9 | |
| SCHEMBL9240128 | 0.77 | MAPK1 (0.32) | ALDH1A1SMYD3DHODHMAPK1 | |
| SCHEMBL7576379 | 0.77 | PDE2A (0.32) | DHODHMAPK1 | |
| SCHEMBL8649601 | 0.76 | NR1H4 (0.35) | ALDH1A1KDM4EHPGDSMYD3DHODH | |
| SCHEMBL9422376 | 0.76 | DHODH (0.34) | DHODHPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0674629-B1 | 4-BENZOYL ISOXAZOLES DERIVATIVES AND THEIR USE AS HERBICIDES | RHONE POULENC AGRICULTURE (GB) | 1998-07-08 | — | — | EP | claimed |