SCHEMBL9422376

SCHEMBL9422376

CS(=O)(=O)Oc1cc(Br)ccc1C(=O)c1cnoc1C1CC1

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 3/20 0.34
SLC6A4 P31645 2/20 0.32
PDE2A O00408 1/20 0.32
POLB P06746 1/20 0.31
EPHX2 P34913 1/20 0.31
PTGDR2 Q9Y5Y4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9323637 0.87 STAT3 (0.35) DHODHPDE2AEPHX2
SCHEMBL9323629 0.85 DHODH (0.35) DHODHPDE2APOLBEPHX2
SCHEMBL6054844 0.83 DHODH (0.35) DHODHPDE2APOLBEPHX2
SCHEMBL6054845 0.80 DHODH (0.33) DHODHPDE2APOLB
SCHEMBL9324399 0.80 CDK1 (0.39) DHODHPOLBPTGDR2
SCHEMBL8492072 0.80 DHODH (0.38) DHODHPDE2APOLBEPHX2
SCHEMBL8747845 0.79 FLT1 (0.36) DHODHPDE2A
SCHEMBL7555068 0.79 L3MBTL1 (0.34) DHODHPDE2A
SCHEMBL9324479 0.78 DHODH (0.38) DHODHEPHX2
SCHEMBL8747841 0.78 PDE2A (0.32) DHODHPDE2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-6271554-A None JP disclosed
JP-H06271554-A HERBICIDE RHONE POULENC AGRICULTURE LTD 1994-09-27 JP disclosed