Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | FPR3 | P25089 | 1/20 | 0.32 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8657068 | 0.96 | MAOB (0.33) | SMN1; SMN2MAOBDAOFPR3FPR2 | |
| SCHEMBL8661603 | 0.92 | MAOB (0.33) | SMN1; SMN2MAOBALDH1A1DAOTP53 | |
| SCHEMBL8656723 | 0.89 | SMN1; SMN2 (0.38) | SMN1; SMN2KDM4EALDH1A1FPR3FPR2 | |
| SCHEMBL8655169 | 0.89 | MAOB (0.35) | SMN1; SMN2MAOBDAOHTR4 | |
| SCHEMBL8659057 | 0.88 | SMN1; SMN2 (0.37) | SMN1; SMN2KDM4EALDH1A1HDAC1EHMT1 | |
| SCHEMBL8661335 | 0.87 | CYP1A2 (0.35) | SMN1; SMN2MAOBDAOHTR4 | |
| SCHEMBL8654817 | 0.87 | HDAC1 (0.33) | SMN1; SMN2HDAC1EHMT1HDAC6HTR4 | |
| SCHEMBL8658456 | 0.85 | GAA (0.34) | SMN1; SMN2KDM4EALDH1A1FPR3FPR2 | |
| SCHEMBL8659278 | 0.84 | SMN1; SMN2 (0.39) | SMN1; SMN2KDM4EALDH1A1TP53 | |
| SCHEMBL8661588 | 0.84 | SMN1; SMN2 (0.40) | SMN1; SMN2KDM4EALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776937-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-07-07 | — | — | US | disclosed |