Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 4/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP3 | P08254 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8657068 | 0.92 | MAOB (0.33) | MAOBDAOHTR4TP53SMN1; SMN2 | |
| SCHEMBL8655104 | 0.92 | SMN1; SMN2 (0.36) | MAOBDAOHTR4ALDH1A1TP53 | |
| SCHEMBL8659077 | 0.89 | GAA (0.34) | ALDH1A1 | |
| SCHEMBL8654695 | 0.87 | HRH3 (0.32) | CYP1A2CYP3A4CYP2D6CYP2C9TSHR | |
| SCHEMBL8656293 | 0.86 | OPRL1 (0.35) | — | |
| SCHEMBL8655169 | 0.85 | MAOB (0.35) | MAOBDAOCYP1A2HTR4SMN1; SMN2 | |
| SCHEMBL8661335 | 0.85 | CYP1A2 (0.35) | MAOBDAOCYP1A2HTR4SMN1; SMN2 | |
| SCHEMBL8655698 | 0.84 | GAA (0.32) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL8654546 | 0.83 | SMN1; SMN2 (0.32) | SIGMAR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8654817 | 0.83 | HDAC1 (0.33) | SIGMAR1HTR4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776937-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-07-07 | — | — | US | disclosed |