Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8655707 | 0.96 | MAPK1 (0.34) | MAPK1CYP1A2SMN1; SMN2ITGB3ITGA2B | |
| SCHEMBL8659526 | 0.95 | ITGB3 (0.35) | MAPK1CYP1A2SMN1; SMN2ITGB3ITGA2B | |
| SCHEMBL8657958 | 0.94 | ITGB3 (0.32) | MAPK1ITGB3ITGA2B | |
| SCHEMBL8657859 | 0.92 | ITGB3 (0.32) | MAPK1ITGB3ITGA2B | |
| SCHEMBL8659258 | 0.91 | ITGB3 (0.33) | ITGB3ITGA2B | |
| SCHEMBL8657293 | 0.90 | ITGB3 (0.34) | MAPK1CYP1A2SMN1; SMN2ITGB3ITGA2B | |
| SCHEMBL8655132 | 0.90 | ITGB3 (0.33) | MAPK1SMN1; SMN2ITGB3ITGA2B | |
| SCHEMBL8656430 | 0.89 | ITGB3 (0.35) | MAPK1CYP1A2SMN1; SMN2ITGB3ITGA2B | |
| SCHEMBL8657674 | 0.89 | CHRM1 (0.34) | MAPK1CYP1A2SMN1; SMN2ITGB3ITGA2B | |
| SCHEMBL8655552 | 0.89 | SMN1; SMN2 (0.34) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776937-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-07-07 | — | — | US | disclosed |