Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8655496 | 0.88 | POLB (0.33) | POLB | |
| SCHEMBL8676080 | 0.87 | POLB (0.33) | POLB | |
| SCHEMBL8651639 | 0.86 | SIGMAR1 (0.33) | — | |
| SCHEMBL8650975 | 0.86 | CNR2 (0.35) | POLB | |
| SCHEMBL8668056 | 0.86 | KDM2B (0.34) | POLB | |
| SCHEMBL8655163 | 0.85 | POLB (0.32) | POLB | |
| SCHEMBL8648885 | 0.85 | POLB (0.30) | POLB | |
| SCHEMBL8655430 | 0.85 | F2 (0.32) | POLB | |
| SCHEMBL8666560 | 0.85 | POLB (0.33) | POLB | |
| SCHEMBL8655292 | 0.85 | POLB (0.32) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5712279-A | Inhibitors of microsomal triglyceride transfer protein and method | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-01-27 | — | — | US | disclosed |