SCHEMBL86554

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL86229	0.84	GRM5 (0.47)	AHRMAOAMAPTKDM4EALDH1A1
	SCHEMBL17433225	0.72	AHR (0.65)	AHRMAOAMAPTKDM4EALDH1A1
	SCHEMBL16919496	0.72	AHR (0.71)	AHRMAOAMAPTKDM4EALDH1A1
	SCHEMBL571563	0.72	AHR (0.71)	AHRMAOAMAPTKDM4EALDH1A1
	SCHEMBL86553	0.72	MAPT (0.48)	MAOAMAPTKDM4EALDH1A1HPGD
	SCHEMBL86315	0.72	MAOA (0.50)	MAOAMAPTKDM4EALDH1A1HPGD
	SCHEMBL1635601	0.70	AHR (0.68)	AHRMAOAMAPTKDM4EALDH1A1
	SCHEMBL87204	0.70	AHR (0.45)	AHRMAOAMAPTKDM4EALDH1A1
	SCHEMBL17433185	0.69	AHR (0.61)	AHRMAOAMAPTKDM4EALDH1A1
	SCHEMBL17433224	0.69	AHR (0.61)	AHRMAOAMAPTKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.