SCHEMBL8655463

SCHEMBL8655463

C=CCc1cc(C(C)Cc2ccccc2)ccc1O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 6/20 0.47
GABRB2 P47870 6/20 0.47
POLB P06746 3/20 0.46
MEN1 O00255 2/20 0.43
GAA P10253 2/20 0.43
MAPT P10636 2/20 0.43
CNR1 P21554 2/20 0.43
CNR2 P34972 2/20 0.43
KMT2A Q03164 2/20 0.43
ALOX5 P09917 1/20 0.43
GABRB1 P18505 1/20 0.43
RXRA P19793 1/20 0.43
GABRA5 P31644 1/20 0.43
GABRA3 P34903 1/20 0.43
GABRA2 P47869 1/20 0.43
ACE2 Q9BYF1 1/20 0.43
SIRT3 Q9NTG7 1/20 0.43
AKR1B1 P15121 2/20 0.42
ESR1 P03372 1/20 0.41
ESR2 Q92731 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10697874 0.93 GABRA1 (0.51) GABRA1GABRB2POLBMEN1GAA
SCHEMBL5176699 0.92 GABRA1 (0.47) GABRA1GABRB2POLBMEN1GAA
SCHEMBL30876823 0.89 GABRA1 (0.50) GABRA1GABRB2POLBMEN1GAA
SCHEMBL8419815 0.79 POLB (0.50) GABRA1GABRB2POLBMEN1GAA
SCHEMBL9816379 0.79 GABRA1 (0.59) GABRA1GABRB2POLBMEN1GAA
SCHEMBL457817 0.79 GABRA1 (0.59) GABRA1GABRB2POLBMEN1GAA
SCHEMBL29386569 0.79 GABRA1 (0.59) GABRA1GABRB2POLBMEN1GAA
SCHEMBL9407589 0.79 ESR1 (0.39) GABRA1GABRB2POLBMEN1GAA
SCHEMBL28427277 0.78 GABRA1 (0.54) GABRA1GABRB2POLBMEN1GAA
SCHEMBL16973200 0.76 ESR1 (0.49) POLBESR1ESR2MAPK1ADRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5811368-A BASIC LEUCO DYE, PHENOLIC COLOR DEVELOPER; IMPROVED STABILITY TO PLASTICIZERS NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1998-09-22 US disclosed
US-5747414-A SUBSTRATE WITH COLOR LAYER, ALUMINUM HYDROXIDE AND A RESIN OF UREA-FORMALDEHYDE AND DEVELOPERS NIPPON PAPER INDUSTRIES, LTD. (JP) 1998-05-05 US disclosed