Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 7/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.37 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9243197 | 0.85 | NISCH (0.44) | SCN10AKCNH2SCN1ASCN5ASCN9A | |
| Butylamine SCHEMBL8655783 | 0.84 | TLR8 (0.46) | CYP19A1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| Butylamine SCHEMBL8653267 | 0.81 | TLR8 (0.44) | CYP19A1GAAMAPTALDH1A1 | |
| Butylamine SCHEMBL8653380 | 0.79 | TLR8 (0.44) | KCNH2NPC1RAB9A | |
| Butylamine SCHEMBL8653466 | 0.78 | TLR8 (0.42) | CYP19A1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL16439282 | 0.78 | CYP19A1 (0.58) | CYP19A1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| Butylamine SCHEMBL8653580 | 0.72 | TLR8 (0.50) | CYP19A1CYP1A2CYP2D6CYP2C19CYP3A4 | |
| SCHEMBL8655655 | 0.71 | SLC7A5 (0.39) | SCN10AKCNH2SCN5APRMT6SLC7A5 | |
| Butylamine SCHEMBL8653688 | 0.70 | TLR8 (0.47) | CYP19A1CYP2D6CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL5672965 | 0.69 | XDH (0.51) | SCN10AKCNH2XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680967-B1 | Erythromycin derivatives, their process of preparation and their use as medicaments | HOECHST MARION ROUSSEL INC (FR) | 1998-10-14 | — | — | EP | claimed |
| EP-0680967-A1 | Erythromycin derivatives, their process of preparation and their use as medicaments | ROUSSEL-UCLAF (FR) | 1995-11-08 | — | — | EP | claimed |
| EP-0680967-B1 | Erythromycin derivatives, their process of preparation and their use as medicaments | HOECHST MARION ROUSSEL INC (FR) | 1998-10-14 | — | — | EP | disclosed |
| EP-0680967-A1 | Erythromycin derivatives, their process of preparation and their use as medicaments | ROUSSEL-UCLAF (FR) | 1995-11-08 | — | — | EP | disclosed |