SCHEMBL8655706

SCHEMBL8655706

COC(=O)Nc1cccc(O)c1C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 0.53
CA1 P00915 5/20 0.53
CA2 P00918 5/20 0.53
CA7 P43166 5/20 0.53
CA9 Q16790 5/20 0.53
CA14 Q9ULX7 5/20 0.53
PLK1 P53350 1/20 0.48
PLK3 Q9H4B4 1/20 0.48
LPAR2 Q9HBW0 1/20 0.44
LPAR3 Q9UBY5 1/20 0.44
HPGD P15428 3/20 0.43
THRB P10828 1/20 0.42
PLAU P00749 1/20 0.41
ALDH1A1 P00352 1/20 0.41
LMNA P02545 1/20 0.41
ALOX15 P16050 1/20 0.41
HSD17B10 Q99714 1/20 0.41
MEN1 O00255 1/20 0.41
HTT P42858 1/20 0.41
KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8657531 0.84 ALDH1A1 (0.56) CA12CA1CA2CA7CA9
SCHEMBL29106089 0.84 CA12 (0.47) CA12CA1CA2CA7CA9
SCHEMBL8652685 0.84 CA12 (0.56) CA12CA1CA2CA7CA9
SCHEMBL8654626 0.84 GAA (0.56) CA12CA1CA2CA7CA9
SCHEMBL10490004 0.83 KDM4E (0.56) CA12CA1CA2CA7CA9
SCHEMBL4959476 0.82 CA12 (0.57) CA12CA1CA2CA7CA9
SCHEMBL8655082 0.82 TRPV1 (0.55) CA12CA1CA2CA7CA9
SCHEMBL8655078 0.82 PLK1 (0.51) CA12CA1CA2CA7CA9
SCHEMBL8654580 0.82 HTT (0.51) CA12CA1CA2CA7CA9
SCHEMBL9153721 0.81 KMT2A (0.54) HPGDALDH1A1MEN1HTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0630758-B1 Heat-sensitive recording material MITSUBISHI PAPER MILLS LTD (JP) 1998-10-07 EP disclosed
US-5466655-A STORAGE STABILITY MITSUBISHI PAPER MILLS LIMITED (JP) 1995-11-14 US disclosed
EP-0630758-A2 Heat-sensitive recording material MITSUBISHI PAPER MILLS, LTD. (JP) 1994-12-28 EP disclosed