Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 20/20 | 0.90 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.74 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.74 |
| ▸ | PRKACA | P17612 | 2/20 | 0.74 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.74 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.74 |
| ▸ | MINK1 | Q8N4C8 | 2/20 | 0.74 |
| ▸ | MAP4K5 | Q9Y4K4 | 2/20 | 0.74 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.74 |
| ▸ | PRKCB | P05771 | 1/20 | 0.74 |
| ▸ | PRKCA | P17252 | 1/20 | 0.74 |
| ▸ | BRDT | Q58F21 | 3/20 | 0.67 |
| ▸ | BRD4 | O60885 | 2/20 | 0.67 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.66 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.66 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.66 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.66 |
| ▸ | PRKCG | P05129 | 1/20 | 0.66 |
| ▸ | LCK | P06239 | 1/20 | 0.66 |
| ▸ | LYN | P07948 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4916756 | 0.95 | MAPK14 (1.00) | MAPK14PRKD3MAP4K4PRKACACSNK1A1 | |
| SCHEMBL4585589 | 0.90 | MAPK14 (0.80) | MAPK14PRKD3MAP4K4PRKACACSNK1A1 | |
| SCHEMBL4916783 | 0.86 | MAPK14 (0.81) | MAPK14PRKD3MAP4K4PRKACACSNK1A1 | |
| SCHEMBL4916787 | 0.86 | MAPK14 (0.81) | MAPK14PRKD3MAP4K4PRKACACSNK1A1 | |
| SCHEMBL8655733 | 0.86 | MAPK14 (0.66) | MAPK14PRKD3MAP4K4PRKACACSNK1A1 | |
| SCHEMBL6876637 | 0.86 | MAPK14 (0.82) | MAPK14PRKD3MAP4K4PRKACACSNK1A1 | |
| Sb-242235 SCHEMBL2267209 | 0.85 | MAPK14 (1.00) | MAPK14PRKD3MAP4K4PRKACACSNK1A1 | |
| SCHEMBL6578729 | 0.83 | MAPK14 (0.79) | MAPK14PRKD3MAP4K4PRKACACSNK1A1 | |
| Trifluoroacetic Acid SCHEMBL7893693 | 0.83 | MAPK14 (0.69) | MAPK14PRKD3MAP4K4PRKACACSNK1A1 | |
| SCHEMBL4919642 | 0.83 | MAPK14 (1.00) | MAPK14PRKD3MAP4K4PRKACACSNK1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5716955-A | Substituted imidazole compounds | SMITHKLINE BEECHAM CORPORATION (US) | 1998-02-10 | — | — | US | claimed |