SCHEMBL8655899

SCHEMBL8655899

CCCCCc1n[nH]c(CCCCC)c1C

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 5/20 0.38
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
ALDH1A1 P00352 2/20 0.35
PKM P14618 1/20 0.35
HPGD P15428 1/20 0.35
HCAR3 P49019 1/20 0.34
TYMP P19971 2/20 0.33
TKT P29401 1/20 0.33
CETP P11597 1/20 0.33
GAA P10253 2/20 0.33
TSHR P16473 1/20 0.33
MAPK1 P28482 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5363198 0.84 HCAR2 (0.38) HCAR2MEN1KMT2AALDH1A1HCAR3
SCHEMBL28137757 0.80 DYRK1A (0.38) HCAR2ALDH1A1PKMHPGDHCAR3
SCHEMBL19156301 0.77 HCAR2 (0.41) HCAR2ALDH1A1PKMHPGDHCAR3
SCHEMBL15334779 0.75 DYRK1A (0.41) HCAR2ALDH1A1HPGDHCAR3TYMP
SCHEMBL7323862 0.72 GAA (0.45) HCAR2ALDH1A1HCAR3TKTGAA
SCHEMBL27141935 0.72 HCAR2 (0.45) HCAR2ALDH1A1HPGDHCAR3GAA
SCHEMBL11411101 0.72 HCAR2 (0.65) HCAR2HCAR3
SCHEMBL17500332 0.71 MAPT (0.41) HCAR2ALDH1A1HPGDHCAR3TYMP
SCHEMBL6316286 0.71 KMT2A (0.39) HCAR2KMT2AALDH1A1PKMHPGD
SCHEMBL3259241 0.71 HCAR2 (0.40) HCAR2ALDH1A1HPGDHCAR3TYMP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0843665-A1 METHOD OF PREPARING 1,2-DIMETHYL-3,5-DIARYLPYRAZOLIUM METHYLSULPHATES BASF AKTIENGESELLSCHAFT (DE) 1998-05-27 EP disclosed
WO-1997006148-A1 METHOD OF PREPARING 1,2-DIMETHYL-3,5-DIARYLPYRAZOLIUM METHYLSULPHATES BASF AKTIENGESELLSCHAFT (DE) 1997-02-20 WO disclosed