Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TKT | P29401 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7316858 | 0.88 | GAA (0.42) | GAATSHRMAPTMAPK1LMNA | |
| SCHEMBL14782532 | 0.82 | GAA (0.46) | GAATSHRMAPTMAPK1LMNA | |
| SCHEMBL15334779 | 0.79 | DYRK1A (0.41) | GAATSHRMAPTMAPK1LMNA | |
| SCHEMBL7320150 | 0.79 | — | — | |
| SCHEMBL17500332 | 0.78 | MAPT (0.41) | GAATSHRMAPTMAPK1LMNA | |
| Hydrochloric Acid SCHEMBL11445607 | 0.77 | GAA (0.41) | GAALMNAALDH1A1NPC1RAB9A | |
| SCHEMBL3664202 | 0.76 | GAA (0.42) | GAATSHRMAPTMAPK1LMNA | |
| SCHEMBL11969244 | 0.74 | GAA (0.41) | GAATSHRMAPTMAPK1LMNA | |
| SCHEMBL14783012 | 0.74 | GAA (0.41) | GAATSHRMAPTMAPK1LMNA | |
| SCHEMBL4758500 | 0.74 | MAPK1 (0.41) | GAATSHRMAPTMAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0114273-A1 | New pharmacologically active pyrazolopyridines | GRUPPO LEPETIT S.p.A. (IT) | 1984-08-01 | — | — | EP | disclosed |