SCHEMBL8655928

SCHEMBL8655928

CCCCCCCC/C=C\CCCCCCCCOC(=O)N[C@@H](CO)C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 2/20 0.54
FAAH O00519 1/20 0.49
DGKA P23743 1/20 0.48
EPHX1 P07099 1/20 0.46
SLC6A5 Q9Y345 1/20 0.46
TP53 P04637 1/20 0.45
CYP1A2 P05177 1/20 0.45
CYP2D6 P10635 1/20 0.45
MAPT P10636 1/20 0.45
CYP2C9 P11712 1/20 0.45
MAPK1 P28482 1/20 0.45
CYP2C19 P33261 1/20 0.45
CETP P11597 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8655925 1.00 EPHX2 (0.54) EPHX2FAAHDGKAEPHX1SLC6A5
SCHEMBL8655937 1.00 EPHX2 (0.54) EPHX2FAAHDGKAEPHX1SLC6A5
SCHEMBL9854740 0.92 EPHX1 (0.54) EPHX1
SCHEMBL7769026 0.92 EPHX1 (0.54) EPHX1
SCHEMBL7769025 0.92 EPHX1 (0.54) EPHX1
SCHEMBL8657701 0.92 EPHX1 (0.54) EPHX1
SCHEMBL8658518 0.92 EPHX1 (0.54) EPHX1
SCHEMBL8755430 0.90 EPHX2 (0.52) EPHX2FAAHDGKAEPHX1
SCHEMBL8755629 0.90 EPHX2 (0.52) EPHX2FAAHDGKAEPHX1
SCHEMBL8653765 0.90 EPHX2 (0.52) EPHX2FAAHDGKAEPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5714630-A REACTING A SERINE SALT WITH AN ACTIVATED HYDROCARBON DERIVATIVE IN THE PRESENCE OF A PHASE TRANSFER AGENT L'OREAL (FR) 1998-02-03 US disclosed
US-5626855-A AMINE SUBSTITUTED WITH ALKOXYCARBONYL GROUP L'OREAL (FR) 1997-05-06 US disclosed
EP-0682011-B1 New derivatives of serine, their preparation and their use in cosmetic and dermatologic compositions OREAL (FR) 1997-04-23 EP disclosed
EP-0682011-A1 New derivatives of serine, their preparation and their use in cosmetic and dermatologic compositions L'OREAL (FR) 1995-11-15 EP disclosed