Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 12/20 | 0.49 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.46 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7769026 | 1.00 | EPHX1 (0.54) | EPHX1ACHENOD1TGFBR1 | |
| SCHEMBL8657701 | 1.00 | EPHX1 (0.54) | EPHX1ACHENOD1TGFBR1 | |
| SCHEMBL8658518 | 1.00 | EPHX1 (0.54) | EPHX1ACHENOD1TGFBR1 | |
| SCHEMBL7769025 | 1.00 | EPHX1 (0.54) | EPHX1ACHENOD1TGFBR1 | |
| SCHEMBL2332506 | 0.93 | TGFBR1 (0.47) | EPHX1ACHETGFBR1 | |
| SCHEMBL5765667 | 0.93 | TGFBR1 (0.47) | EPHX1ACHETGFBR1 | |
| SCHEMBL1840799 | 0.93 | TGFBR1 (0.47) | EPHX1ACHETGFBR1 | |
| SCHEMBL8655928 | 0.92 | EPHX2 (0.54) | EPHX1 | |
| SCHEMBL8655937 | 0.92 | EPHX2 (0.54) | EPHX1 | |
| SCHEMBL8655925 | 0.92 | EPHX2 (0.54) | EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0408448-A1 | Urethane derivatives, their preparation and their use as humectants in cosmetic and pharmaceutical compositions for the treatment of dry skin | L'OREAL (FR) | 1991-01-16 | — | — | EP | disclosed |