SCHEMBL8655992

SCHEMBL8655992

[O]Cc1cc(OCc2cc(OCc3ccccc3)cc(OCc3ccccc3)c2)cc(OCc2cc(OCc3ccccc3)cc(OCc3ccccc3)c2)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.61
KMT2A Q03164 2/20 0.61
MAOB P27338 7/20 0.53
ALOX5 P09917 1/20 0.52
GSTP1 P09211 1/20 0.50
CYP4F2 P78329 1/20 0.50
CYP4A11 Q02928 1/20 0.50
BCHE P06276 1/20 0.50
LMNA P02545 1/20 0.50
CYP1A2 P05177 1/20 0.50
PTGS1 P23219 1/20 0.50
SLC6A2 P23975 1/20 0.50
CYP2C19 P33261 1/20 0.50
PTGS2 P35354 1/20 0.50
SLC6A3 Q01959 1/20 0.50
HIF1A Q16665 1/20 0.50
HDAC6 Q9UBN7 1/20 0.50
MAOA P21397 3/20 0.49
L3MBTL1 Q9Y468 3/20 0.49
NR4A2 P43354 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4910007 0.98 MEN1 (0.62) MEN1KMT2AMAOBALOX5GSTP1
SCHEMBL4674930 0.85 MEN1 (0.70) MEN1KMT2AMAOBALOX5GSTP1
SCHEMBL27409859 0.85 BCHE (0.64) MEN1KMT2AMAOBALOX5CYP4F2
SCHEMBL21401398 0.85 MEN1 (0.56) MEN1KMT2AMAOBALOX5GSTP1
SCHEMBL5329319 0.84 MAOB (0.72) MEN1KMT2AMAOBALOX5CYP4F2
SCHEMBL27588719 0.83 BCHE (0.62) MAOBALOX5CYP4F2CYP4A11BCHE
SCHEMBL15761346 0.82 LMNA (0.61) MEN1KMT2AMAOBALOX5GSTP1
SCHEMBL5027658 0.81 MEN1 (0.56) MEN1KMT2AMAOBALOX5GSTP1
SCHEMBL20994140 0.81 MEN1 (0.56) MEN1KMT2AMAOBALOX5GSTP1
SCHEMBL13241481 0.81 MEN1 (0.56) MEN1KMT2AMAOBALOX5GSTP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5807837-A ADMINISTERING TO TREAT HIV INFECTIONS TO INHIBIT THE REPLICATION OF FOREIGN NUCLEIC ACIDS IN A NORMAL CELL SANKYO COMPANY, LIMITED (JP) 1998-09-15 US claimed
US-5674856-A TREATMENT AND PROPHYLAXIS OF VIRAL INFECTIONS, INCLUDING AIDS AND TUMORS SANKYO COMPANY, LIMITED (JP) 1997-10-07 US claimed
EP-0611075-B1 Modified oligodeoxyribonucleotides, their preparation and their therapeutic use SANKYO CO (JP) 1996-12-18 EP claimed
EP-0611075-A1 Modified oligodeoxyribonucleotides, their preparation and their therapeutic use SANKYO COMPANY LIMITED (JP) 1994-08-17 EP claimed
EP-0611075-B1 Modified oligodeoxyribonucleotides, their preparation and their therapeutic use SANKYO CO (JP) 1996-12-18 EP disclosed
EP-0611075-A1 Modified oligodeoxyribonucleotides, their preparation and their therapeutic use SANKYO COMPANY LIMITED (JP) 1994-08-17 EP disclosed