Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 1/20 | 0.59 |
| ▸ | TK1 | P04183 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8656005 | 1.00 | TYMS (0.59) | TYMSTK1POLB | |
| SCHEMBL8655467 | 0.93 | TYMS (0.66) | TYMSTK1POLB | |
| SCHEMBL8527785 | 0.92 | TK1 (0.64) | TYMSTK1POLB | |
| SCHEMBL9550743 | 0.92 | TK1 (0.64) | TYMSTK1POLB | |
| SCHEMBL8657843 | 0.88 | TK1 (0.54) | TYMSTK1POLB | |
| SCHEMBL8657842 | 0.88 | TK1 (0.54) | TYMSTK1POLB | |
| SCHEMBL9017682 | 0.88 | TK1 (0.53) | TYMSTK1 | |
| SCHEMBL8656935 | 0.88 | TYMS (0.58) | TYMSTK1POLB | |
| SCHEMBL8656937 | 0.88 | TYMS (0.58) | TYMSTK1POLB | |
| SCHEMBL8657316 | 0.85 | POLB (0.54) | TK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5807837-A | ADMINISTERING TO TREAT HIV INFECTIONS TO INHIBIT THE REPLICATION OF FOREIGN NUCLEIC ACIDS IN A NORMAL CELL | SANKYO COMPANY, LIMITED (JP) | 1998-09-15 | — | — | US | disclosed |
| US-5674856-A | TREATMENT AND PROPHYLAXIS OF VIRAL INFECTIONS, INCLUDING AIDS AND TUMORS | SANKYO COMPANY, LIMITED (JP) | 1997-10-07 | — | — | US | disclosed |
| EP-0611075-B1 | Modified oligodeoxyribonucleotides, their preparation and their therapeutic use | SANKYO CO (JP) | 1996-12-18 | — | — | EP | disclosed |
| EP-0611075-A1 | Modified oligodeoxyribonucleotides, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1994-08-17 | — | — | EP | disclosed |