Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 8/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.44 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.44 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.43 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.41 |
| ▸ | CHRNG | P07510 | 1/20 | 0.41 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.41 |
| ▸ | CHRND | Q07001 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9772173 | 1.00 | GRIA1 (0.47) | GRIA1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| Gusperimus SCHEMBL28026 | 1.00 | GRIA1 (0.47) | GRIA1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL9772156 | 1.00 | GRIA1 (0.47) | GRIA1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL9688242 | 1.00 | GRIA1 (0.47) | GRIA1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL25482108 | 0.99 | GRIA1 (0.46) | GRIA1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| Gusperimus SCHEMBL12980163 | 0.99 | GRIA1 (0.46) | GRIA1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| Gusperimus SCHEMBL26925 | 0.99 | GRIA1 (0.46) | GRIA1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| Gusperimus SCHEMBL317912 | 0.99 | GRIA1 (0.46) | GRIA1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| Hydrochloric Acid SCHEMBL9772186 | 0.99 | GRIA1 (0.46) | GRIA1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| Hydrochloric Acid SCHEMBL9772231 | 0.99 | GRIA1 (0.46) | GRIA1CHRNB2CHRNB4CHRNA3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755380-B1 | 15-DEOXYSPERGUALIN ANALOGS, THERAPEUTICAL USE THEREOF, AND METHOD FOR PREPARING SAME | FOURNIER IND & SANTE (FR) | 1998-10-14 | — | — | EP | disclosed |