Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | ACLY | P53396 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8661509 | 0.89 | HPGD (0.53) | HPGDTDP1POLBALDH1A1MAPT | |
| SCHEMBL8657916 | 0.88 | HPGD (0.48) | HPGDTDP1POLBALDH1A1MAPT | |
| SCHEMBL8656136 | 0.88 | HPGD (0.50) | HPGDTDP1POLBALDH1A1MAPT | |
| SCHEMBL8662978 | 0.87 | HPGD (0.46) | HPGDTDP1POLBALDH1A1MAPT | |
| SCHEMBL8656177 | 0.87 | HPGD (0.47) | HPGDTDP1POLBALDH1A1MAPT | |
| SCHEMBL8661926 | 0.86 | HPGD (0.45) | HPGDTDP1POLBALDH1A1MAPT | |
| SCHEMBL8660883 | 0.85 | HPGD (0.50) | HPGDTDP1POLBALDH1A1MAPT | |
| SCHEMBL8661718 | 0.85 | HPGD (0.46) | HPGDTDP1POLBALDH1A1MAPT | |
| SCHEMBL8659094 | 0.84 | HPGD (0.51) | HPGDTDP1POLBALDH1A1MAPT | |
| SCHEMBL8660042 | 0.84 | HPGD (0.53) | HPGDTDP1POLBALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739166-A | ALKYLSULFONYL OR AMINOSULFONYL SUBSTITUTED AROMATIC COMPOUNDS AS NON-STEROIDAL ANTIINFLAMMATORY AGENT | G.D. SEARLE & CO. (US) | 1998-04-14 | — | — | US | disclosed |