Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 5/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYTH2 | Q99418 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | EDNRB | P24530 | 1/20 | 0.41 |
| ▸ | EDNRA | P25101 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8661509 | 0.92 | HPGD (0.53) | HPGDSLC40A1GAAALOX15HSD17B10 | |
| SCHEMBL8661655 | 0.89 | HPGD (0.48) | HPGDSLC40A1GAAALOX15HSD17B10 | |
| SCHEMBL8656136 | 0.88 | HPGD (0.50) | HPGDGAAHSD17B10TSHRPOLB | |
| SCHEMBL8661048 | 0.88 | HPGD (0.50) | HPGDSLC40A1GAAALOX15HSD17B10 | |
| SCHEMBL8661239 | 0.88 | HPGD (0.52) | HPGDSLC40A1GAAALOX15HSD17B10 | |
| SCHEMBL8659094 | 0.87 | HPGD (0.51) | HPGDGAAPOLBFFAR4ALDH1A1 | |
| SCHEMBL8660153 | 0.87 | HPGD (0.53) | HPGDSLC40A1GAAPOLBALDH1A1 | |
| SCHEMBL8660042 | 0.87 | HPGD (0.53) | HPGDSLC40A1GAAPOLBFFAR4 | |
| SCHEMBL8661170 | 0.86 | HPGD (0.48) | HPGDSLC40A1GAAALOX15HSD17B10 | |
| SCHEMBL8661257 | 0.86 | HPGD (0.48) | HPGDHSD17B10TSHRPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739166-A | ALKYLSULFONYL OR AMINOSULFONYL SUBSTITUTED AROMATIC COMPOUNDS AS NON-STEROIDAL ANTIINFLAMMATORY AGENT | G.D. SEARLE & CO. (US) | 1998-04-14 | — | — | US | disclosed |