Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | PPARD | Q03181 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11796292 | 0.84 | — | — | |
| SCHEMBL9698611 | 0.83 | LPAR3 (0.46) | TDP1TP53 | |
| SCHEMBL9697474 | 0.83 | LPAR3 (0.46) | TDP1TP53 | |
| SCHEMBL9698684 | 0.83 | LPAR3 (0.46) | TDP1TP53 | |
| SCHEMBL9697844 | 0.83 | LPAR3 (0.46) | TDP1TP53 | |
| SCHEMBL9698688 | 0.82 | TP53 (0.50) | TDP1TP53TSHRPPARD | |
| SCHEMBL8656736 | 0.80 | PPARD (0.52) | TDP1TP53TSHRPPARD | |
| SCHEMBL9701956 | 0.76 | LPAR3 (0.42) | TDP1TP53TSHRPPARDALDH1A1 | |
| SCHEMBL13239564 | 0.75 | LPAR3 (0.44) | TDP1TP53TSHRALDH1A1 | |
| SCHEMBL9701979 | 0.75 | LPAR3 (0.44) | TDP1TP53TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5728686-A | TREATMENT OF MUSCULAR DYSTROPHY | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-03-17 | — | — | US | disclosed |