Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HPN | P05981 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL692775 | 0.79 | ELANE (0.68) | ELANEMEN1ALDH1A1KMT2AHPN | |
| SCHEMBL692861 | 0.79 | ELANE (0.68) | ELANEMEN1ALDH1A1KMT2AHPN | |
| SCHEMBL693158 | 0.76 | ELANE (0.64) | ELANEMEN1ALDH1A1KMT2AHPN | |
| SCHEMBL12352004 | 0.74 | ELANE (0.70) | ELANEMEN1KMT2A | |
| SCHEMBL30366029 | 0.74 | ELANE (0.60) | ELANEMEN1ALDH1A1KMT2AHPN | |
| SCHEMBL692767 | 0.74 | ELANE (0.60) | ELANEMEN1ALDH1A1KMT2AHPN | |
| SCHEMBL692229 | 0.72 | ELANE (0.66) | ELANEMEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL12758386 | 0.71 | ELANE (0.70) | ELANEMEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL4117968 | 0.71 | ELANE (1.00) | ELANEMEN1ALDH1A1KMT2ALMNA | |
| SCHEMBL258516 | 0.70 | KMT2A (0.62) | ELANEMEN1ALDH1A1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828721-A1 | 2-AMINO-BENZOXAZINONES FOR THE TREATMENT OF VIRAL INFECTIONS | G.D. SEARLE & CO. (US) | 1998-03-18 | — | — | EP | claimed |