SCHEMBL12352004

SCHEMBL12352004

Cc1nc2ccc(O)cc2c(=O)o1

nearest known ligand 0.70

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ELANE P08246 8/20 0.70
MAPT P10636 2/20 0.52
HSD17B10 Q99714 1/20 0.52
MEN1 O00255 1/20 0.51
RAB9A P51151 1/20 0.51
KMT2A Q03164 1/20 0.51
TDP1 Q9NUW8 1/20 0.51
ESR1 P03372 3/20 0.46
ESR2 Q92731 3/20 0.46
PDE2A O00408 1/20 0.46
HSD17B3 P37058 2/20 0.45
APP P05067 1/20 0.42
ESRRB O95718 1/20 0.42
ESRRA P11474 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4117968 0.82 ELANE (1.00) ELANEMAPTMEN1RAB9AKMT2A
SCHEMBL692229 0.80 ELANE (0.66) ELANEMEN1RAB9AKMT2ATDP1
SCHEMBL3539033 0.79 ELANE (0.70) ELANEMEN1KMT2A
SCHEMBL1812732 0.79 ELANE (0.70) ELANEMEN1KMT2A
SCHEMBL31000399 0.79 ELANE (0.70) ELANEMEN1KMT2A
SCHEMBL4123057 0.79 ELANE (0.70) ELANEMEN1KMT2A
SCHEMBL12758386 0.79 ELANE (0.70) ELANEMAPTHSD17B10MEN1RAB9A
SCHEMBL12847193 0.79 ELANE (0.70) ELANEMEN1RAB9AKMT2A
SCHEMBL3541523 0.79 ELANE (0.70) ELANEMAPTMEN1KMT2ATDP1
SCHEMBL757536 0.79 ELANE (0.72) ELANEMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8541488-B2 Formed resin article and polymer film FUJIFILM CORPORATION (JP) 2013-09-24 US disclosed
US-8541488-B2 Formed resin article and polymer film FUJIFILM CORPORATION (JP) 2013-09-24 US disclosed
US-20110186791-A1 ULTRAVIOLET ABSORBENT COMPOSITION FUJIFILM CORPORATION (JP) 2011-08-04 US disclosed
US-20110186791-A1 ULTRAVIOLET ABSORBENT COMPOSITION FUJIFILM CORPORATION (JP) 2011-08-04 US disclosed
US-20110092619-A1 FORMED RESIN ARTICLE AND POLYMER FILM FUJIFILM CORPORATION (JP) 2011-04-21 US disclosed
US-20110092619-A1 FORMED RESIN ARTICLE AND POLYMER FILM FUJIFILM CORPORATION (JP) 2011-04-21 US disclosed
US-7897761-B2 Heterocyclic compound FUJIFILM CORPORATION (JP) 2011-03-01 US disclosed
US-7897761-B2 Heterocyclic compound FUJIFILM CORPORATION (JP) 2011-03-01 US disclosed
US-20110024701-A1 Ultraviolet Absorbent Composition FUJIFILM CORPORATION (JP) 2011-02-03 US disclosed
US-20110024701-A1 Ultraviolet Absorbent Composition FUJIFILM CORPORATION (JP) 2011-02-03 US disclosed
EP-2272935-A1 ULTRAVIOLET ABSORBENT COMPOSITIONS FUJIFILM Corporation (JP) 2011-01-12 EP disclosed
US-20100004439-A1 Heterocyclic Compound FUJIFLM CORPORATION (JP) 2010-01-07 US disclosed
US-20100004439-A1 Heterocyclic Compound FUJIFLM CORPORATION (JP) 2010-01-07 US disclosed
US-20090239982-A1 Ultraviolet Absorbent and Heterocyclic Compound FUJIFILM CORPORATION (JP) 2009-09-24 US disclosed
US-20090239982-A1 Ultraviolet Absorbent and Heterocyclic Compound FUJIFILM CORPORATION (JP) 2009-09-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090239982-A1 Ultraviolet Absorbent and Heterocyclic Compound CYP2A6, CYP2B6, XPO6 ELANE 1479/4885MAPT 4345/4885HSD17B10 2200/4885
US-20100004439-A1 Heterocyclic Compound PTGER1, CYP1A1, ALOX12 ELANE 1343/4885MAPT 4807/4885HSD17B10 264/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.