SCHEMBL8656281

SCHEMBL8656281

C=C(C)C(=O)OCCOC(=O)C(Cl)(Cl)Cl

nearest known ligand 0.55

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.55
TSHR P16473 4/20 0.48
ALDH1A1 P00352 3/20 0.39
POLB P06746 1/20 0.37
APEX1 P27695 1/20 0.37
HTT P42858 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL751055 0.86 THRB (0.53) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL11684093 0.85 THRB (0.52) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL15636 0.82 THRB (0.74) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL6142874 0.82 THRB (0.74) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL11106417 0.82 THRB (0.57) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL3286289 0.80 THRB (0.71) THRBTSHRALDH1A1POLBAPEX1
Ethylene SCHEMBL619217 0.80 THRB (0.71) THRBTSHRALDH1A1POLBAPEX1
Ethylene SCHEMBL9301341 0.80 THRB (0.71) THRBTSHRALDH1A1POLBAPEX1
Ethylene SCHEMBL955493 0.80 THRB (0.71) THRBTSHRALDH1A1POLBAPEX1
Ethylene SCHEMBL632736 0.80 THRB (0.71) THRBTSHRALDH1A1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0495603-B1 Hydrogel material PILKINGTON BARNES HIND INC (US) 1998-10-14 EP claimed
US-5362768-A Polymers for contact lenses PILKINGTON VISIONCARE, INC. (US) 1994-11-08 US claimed
EP-0495603-A1 Hydrogel material Pilkington Visioncare Inc. (a Delaware corp.) (US) 1992-07-22 EP claimed
US-20080274425-A1 Multilayeer; aluminum support with fluoroalkyl acrylic group containing polymer; alkali soluble resin and an acid generator KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2008-11-06 US disclosed
US-20080274425-A1 Multilayeer; aluminum support with fluoroalkyl acrylic group containing polymer; alkali soluble resin and an acid generator KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2008-11-06 US disclosed
US-7285375-B2 Photosensitive composition, photosensitive lithography plate and method for producing lithography plate KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-10-23 US disclosed
US-7285375-B2 Photosensitive composition, photosensitive lithography plate and method for producing lithography plate KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-10-23 US disclosed
US-20070020555-A1 Photosensitive composition, photosensitive lithography plate and method for producing lithography plate KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-01-25 US disclosed
US-20070020555-A1 Photosensitive composition, photosensitive lithography plate and method for producing lithography plate KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-01-25 US disclosed
EP-0495603-B1 Hydrogel material PILKINGTON BARNES HIND INC (US) 1998-10-14 EP disclosed
US-5077156-A ANTISTATIC AND ELECTRICALLY CONDUCTIVE RELIEF IMAGES, PROCESSES FOR THE PRODUCTION THEREOF, COATING AGENTS AND RADIATION-SENSITIVE POLYMERS CIBA-GEIGY CORPORATION (US) 1991-12-31 US disclosed
US-4448923-A Interpolymer latex, process for its preparation and use of the latex for coating paper RHONE POULENC SPECIALITES CHIMIQUES (FR) 1984-05-15 US disclosed