Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 14/20 | 0.56 |
| ▸ | ACE2 | Q9BYF1 | 9/20 | 0.56 |
| ▸ | LTA4H | P09960 | 2/20 | 0.53 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8656290 | 1.00 | ACE (0.56) | ACEACE2LTA4HF2 | |
| SCHEMBL8652940 | 0.96 | ACE (0.58) | ACEACE2LTA4H | |
| SCHEMBL8652937 | 0.96 | ACE (0.58) | ACEACE2LTA4H | |
| SCHEMBL8654625 | 0.96 | ACE (0.58) | ACEACE2LTA4H | |
| SCHEMBL8654621 | 0.96 | ACE (0.58) | ACEACE2LTA4H | |
| SCHEMBL7441085 | 0.86 | DPP4 (0.46) | ACEACE2F2 | |
| SCHEMBL6438368 | 0.85 | ACE (0.58) | ACEACE2LTA4H | |
| SCHEMBL6438372 | 0.85 | ACE (0.58) | ACEACE2LTA4H | |
| SCHEMBL8378226 | 0.85 | ACE (0.58) | ACEACE2LTA4H | |
| SCHEMBL8655055 | 0.84 | LTA4H (0.59) | ACEACE2LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852051-A | Dipeptide p-amidinobenzylamides with N-terminal sulfonyl or aminosulfonyl radicals | BASF AKTIENGESELLSCHAFT (DE) | 1998-12-22 | — | — | US | disclosed |