Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 3/20 | 0.33 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.33 |
| ▸ | UGCG | Q16739 | 1/20 | 0.33 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.33 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL943074 | 0.74 | MAPT (0.42) | ALOX5APFEN1MRGPRX1SLC6A2SLC6A4 | |
| SCHEMBL27951613 | 0.72 | AR (0.43) | ALOX5APFEN1SLC6A2SLC6A4MEN1 | |
| SCHEMBL28288419 | 0.70 | MAPT (0.52) | ALOX5APFEN1SLC6A2SLC6A4MEN1 | |
| SCHEMBL29635641 | 0.67 | L3MBTL1 (0.48) | ALOX5APFEN1MEN1MAPTKMT2A | |
| SCHEMBL10499330 | 0.67 | L3MBTL1 (0.48) | ALOX5APFEN1MEN1MAPTKMT2A | |
| SCHEMBL9376880 | 0.67 | PDE2A (0.39) | MAPTNPSR1ALDH1A1 | |
| SCHEMBL3804136 | 0.66 | — | — | |
| SCHEMBL2357267 | 0.66 | GAA (0.57) | MEN1MAPTKMT2AS1PR2S1PR4 | |
| SCHEMBL9171200 | 0.66 | CXCL12 (0.37) | MAPTLMNAHTTSMN1; SMN2KDM4E | |
| SCHEMBL3655004 | 0.66 | MAPT (0.44) | ALOX5APFEN1MRGPRX1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0541809-B1 | TRIAZOLE COMPOUND | CHUGAI PHARMACEUTICAL CO LTD (JP) | 1998-11-04 | — | — | EP | disclosed |
| US-5338720-A | Low dosage | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1994-08-16 | — | — | US | disclosed |
| EP-0541809-A1 | TRIAZOLE COMPOUND | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1993-05-19 | — | — | EP | disclosed |