SCHEMBL8657228

SCHEMBL8657228

ClC(Cl)=CCOc1cc(Cl)c(OC2CCc3ccccc32)c(Cl)c1

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.39
TAS1R3 Q7RTX0 7/20 0.38
TAS1R1 Q7RTX1 7/20 0.38
TAS1R2 Q8TE23 6/20 0.38
FFAR1 O14842 3/20 0.36
SLC6A4 P31645 1/20 0.34
RAB9A P51151 1/20 0.33
GFRA2 O00451 1/20 0.33
GFRA3 O60609 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
FABP4 P15090 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8409153 0.78 IDO1 (0.49) IDO1TAS1R3TAS1R1TAS1R2FFAR1
SCHEMBL8407690 0.71 HTT (0.41)
SCHEMBL8408601 0.69 KDM4E (0.41) RAB9AMEN1KMT2A
SCHEMBL8405491 0.68 NR4A2 (0.43) IDO1RAB9AMEN1KMT2AFABP4
SCHEMBL8408702 0.68 KCNA3 (0.41) RAB9A
SCHEMBL13614127 0.67 HTT (0.42) TAS1R3TAS1R1TAS1R2RAB9AMEN1
SCHEMBL8408754 0.67 HTT (0.39) MEN1KMT2A
SCHEMBL8408794 0.67 HTT (0.39) MEN1KMT2A
SCHEMBL8519414 0.67 HPGD (0.38) FFAR1RAB9A
SCHEMBL8407162 0.66 SMN1; SMN2 (0.42) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0722430-B1 DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 1998-10-21 EP disclosed
EP-0722430-A1 DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1996-07-24 EP disclosed
WO-1996004228-A1 DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-02-15 WO disclosed