Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.49 |
| ▸ | DRD1 | P21728 | 5/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD5 | P21918 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.40 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8657228 | 0.78 | IDO1 (0.39) | IDO1TAS1R3TAS1R1TAS1R2SLC6A4 | |
| SCHEMBL8529487 | 0.75 | IDO1 (0.54) | IDO1FFAR1 | |
| SCHEMBL8530467 | 0.75 | IDO1 (0.50) | IDO1FFAR1 | |
| SCHEMBL12320506 | 0.73 | SLC6A4 (0.57) | IDO1TAS1R3TAS1R1MAPK1SLC6A4 | |
| SCHEMBL12320178 | 0.73 | IDO1 (0.51) | IDO1SLC6A4FFAR1 | |
| SCHEMBL12320494 | 0.71 | SLC6A4 (0.51) | IDO1TAS1R3TAS1R1SLC6A4 | |
| SCHEMBL12017975 | 0.71 | IDO1 (0.61) | IDO1SLC6A4FFAR1 | |
| SCHEMBL1746749 | 0.71 | IDO1 (0.49) | IDO1SLC6A4FFAR1 | |
| SCHEMBL9391018 | 0.70 | IDO1 (0.66) | IDO1FFAR1 | |
| SCHEMBL376248 | 0.69 | IDO1 (0.70) | IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5872137-A | AROMATIC OXY DIHALOPRENE COMPOUNDS INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-02-16 | — | — | US | disclosed |
| EP-0722430-B1 | DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL CO (JP) | 1998-10-21 | — | — | EP | disclosed |