SCHEMBL8657287

SCHEMBL8657287

CCCCCCCCCCCCCCCCCOP(=O)(O)OC1CCCC1

nearest known ligand 0.53

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LPAR3 Q9UBY5 9/20 0.53
LPAR2 Q9HBW0 6/20 0.53
LPAR1 Q92633 5/20 0.53
AKT1 P31749 5/20 0.50
MAPK14 Q16539 2/20 0.50
TERT O14746 1/20 0.50
UCHL3 P15374 1/20 0.50
NAAA Q02083 2/20 0.45
AKT2 P31751 3/20 0.43
AKT3 Q9Y243 3/20 0.43
PIK3R1 P27986 2/20 0.43
PIK3CA P42336 2/20 0.43
PLCG2 P16885 1/20 0.43
GAB1 Q13480 1/20 0.43
LPAR5 Q9H1C0 1/20 0.42
P2RY10 O00398 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10534538 0.98 LPAR3 (0.51) LPAR3LPAR2LPAR1AKT1MAPK14
SCHEMBL8657356 0.98 LPAR3 (0.51) LPAR3LPAR2LPAR1AKT1MAPK14
SCHEMBL14468696 0.98 LPAR3 (0.51) LPAR3LPAR2LPAR1AKT1MAPK14
SCHEMBL10781111 0.98 LPAR3 (0.51) LPAR3LPAR2LPAR1AKT1MAPK14
SCHEMBL19917833 0.97 LPAR3 (0.49) LPAR3LPAR2LPAR1AKT1MAPK14
SCHEMBL17169188 0.92 CYP3A4 (0.42) LPAR3LPAR2LPAR1AKT1MAPK14
SCHEMBL29001726 0.86 ACHE (0.39) LPAR3LPAR2LPAR1AKT1MAPK14
SCHEMBL14491950 0.86 LPAR3 (0.43) LPAR3LPAR2LPAR1AKT1MAPK14
SCHEMBL15241630 0.86 LPAR3 (0.43) LPAR3LPAR2LPAR1AKT1MAPK14
SCHEMBL14447874 0.86 AKT1 (0.64) LPAR3LPAR2LPAR1AKT1MAPK14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0531585-B1 Oil additive concentrates and lubricants of enhanced performance capabilities ETHYL PETROLEUM ADDITIVES LTD (GB) 1998-11-04 EP disclosed
US-5464549-A Oil soluble dispersants suitable for use in fuels and lubricants ETHYL CORPORATION (US) 1995-11-07 US disclosed
US-5358652-A Using 3,5-dihydrocarbyl-4-hydroxybenzylamine compound ETHYL PETROLEUM ADDITIVES, LIMITED (GB) 1994-10-25 US disclosed
US-5241003-A Post-treated polyisobutenyl succinimide; crankcase, transmission oils ETHYL PETROLEUM ADDITIVES, INC. (US) 1993-08-31 US disclosed
EP-0531585-A1 Oil additive concentrates and lubricants of enhanced performance capabilities ETHYL PETROLEUM ADDITIVES LIMITED (GB) 1993-03-17 EP disclosed
US-5137980-A Reacting polyisobutene with aacidic reactant; super atmospheric pressure; low tar rating ETHYL PETROLEUM ADDITIVES, INC. (US) 1992-08-11 US disclosed