Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12479809 | 0.86 | HTT (0.55) | HTTPOLBLMNANPC1RAB9A | |
| SCHEMBL11745671 | 0.82 | SMN1; SMN2 (0.43) | HTTPOLBLMNANPC1RAB9A | |
| SCHEMBL2760498 | 0.81 | POLB (0.65) | HTTPOLBLMNANPC1RAB9A | |
| SCHEMBL18354808 | 0.80 | NPC1 (0.56) | HTTPOLBLMNANPC1RAB9A | |
| SCHEMBL16985301 | 0.80 | HTT (0.52) | HTTPOLBLMNANPC1RAB9A | |
| SCHEMBL1520529 | 0.80 | POLB (0.63) | HTTPOLBLMNANPC1RAB9A | |
| SCHEMBL16943099 | 0.79 | NPC1 (0.55) | HTTPOLBLMNANPC1RAB9A | |
| SCHEMBL1521469 | 0.78 | HTT (0.56) | HTTPOLBLMNANPC1RAB9A | |
| SCHEMBL10938829 | 0.77 | HTT (0.50) | HTTPOLBLMNANPC1RAB9A | |
| SCHEMBL2066583 | 0.76 | NPC1 (0.59) | HTTPOLBLMNANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0467707-A1 | Process for the preparation of 1-Hydroxymethylpyrazoles | BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) | 1992-01-22 | — | — | EP | claimed |
| EP-0467708-B1 | Control of microorganisms on plants with 1-hydroxymethylpyrazoles | BUCKMAN LABOR INC (US) | 1998-11-04 | — | — | EP | disclosed |
| EP-0467707-A1 | Process for the preparation of 1-Hydroxymethylpyrazoles | BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) | 1992-01-22 | — | — | EP | disclosed |