Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11751104 | 0.84 | POLB (0.42) | SMN1; SMN2NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL8657291 | 0.82 | HTT (0.57) | SMN1; SMN2NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL3824357 | 0.79 | SMN1; SMN2 (0.38) | SMN1; SMN2NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL9202274 | 0.74 | PKM (0.47) | SMN1; SMN2NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL25174156 | 0.73 | L3MBTL1 (0.34) | SMN1; SMN2NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL25173936 | 0.70 | KMT2A (0.33) | SMN1; SMN2NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL12479809 | 0.69 | HTT (0.55) | SMN1; SMN2NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL28848236 | 0.67 | ALDH1A1 (0.40) | SMN1; SMN2KMT2AMEN1HTTPOLB | |
| SCHEMBL13306214 | 0.65 | HTT (0.46) | SMN1; SMN2NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL8951990 | 0.64 | PKM (0.44) | SMN1; SMN2NPC1RAB9AHTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4025530-A | ABSCISSION OF FRUIT | ABBOTT LABORATORIES (US) | 1977-05-24 | — | — | US | disclosed |
| US-3932453-A | PLANT GROWTH REGULATORS | ABBOTT LABORATORIES (US) | 1976-01-13 | — | — | US | disclosed |