Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGALS9 | O00182 | 1/20 | 0.50 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.50 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.50 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | TYMP | P19971 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | SYNJ2 | O15056 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8603059 | 0.92 | LGALS9 (0.53) | LGALS9LGALS1LGALS3LGALS7; LGALS7BPOLB | |
| SCHEMBL23269817 | 0.92 | LGALS9 (0.53) | LGALS9LGALS1LGALS3LGALS7; LGALS7BPOLB | |
| SCHEMBL27388397 | 0.92 | LGALS9 (0.53) | LGALS9LGALS1LGALS3LGALS7; LGALS7BPOLB | |
| SCHEMBL10359946 | 0.89 | LGALS9 (0.53) | LGALS9LGALS1LGALS3LGALS7; LGALS7BPOLB | |
| SCHEMBL10359947 | 0.89 | LGALS9 (0.53) | LGALS9LGALS1LGALS3LGALS7; LGALS7BPOLB | |
| SCHEMBL5384438 | 0.89 | USP2 (0.56) | LGALS9LGALS1LGALS3LGALS7; LGALS7BPOLB | |
| SCHEMBL15481991 | 0.89 | USP2 (0.56) | LGALS9LGALS1LGALS3LGALS7; LGALS7BPOLB | |
| SCHEMBL8153332 | 0.89 | USP2 (0.56) | LGALS9LGALS1LGALS3LGALS7; LGALS7BPOLB | |
| SCHEMBL13146097 | 0.89 | USP2 (0.56) | LGALS9LGALS1LGALS3LGALS7; LGALS7BPOLB | |
| SCHEMBL8153327 | 0.89 | USP2 (0.56) | LGALS9LGALS1LGALS3LGALS7; LGALS7BPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0739333-B1 | SELECTIVE ASYMMETRIC HYDROGENATION OF DEHYDROAMINO ACID DERIVATIVES USING RHODIUM AND IRIDIUM DIPHOSPHINITE CARBOHYDRATE CATALYST COMPOSITIONS | DU PONT (US) | 1998-10-14 | — | — | EP | disclosed |
| US-5481006-A | PREPARATION OF INTERMEDIATES FOR PHARMACEUTICALS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-01-02 | — | — | US | disclosed |