Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 7/20 | 0.48 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.48 |
| ▸ | GCGR | P47871 | 1/20 | 0.47 |
| ▸ | PNLIP | P16233 | 2/20 | 0.46 |
| ▸ | STK39 | Q9UEW8 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | IL2 | P60568 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 2/20 | 0.43 |
| ▸ | BRAF | P15056 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9720327 | 0.93 | GCGR (0.51) | TLR8TLR7GCGRPNLIPSTK39 | |
| SCHEMBL8658881 | 0.92 | TLR8 (0.47) | TLR8TLR7PNLIPSTK39IL2 | |
| SCHEMBL8656260 | 0.91 | GCGR (0.47) | GCGRPNLIPSTK39KDRBRAF | |
| SCHEMBL8657144 | 0.89 | TLR8 (0.59) | TLR8TLR7GCGRPNLIPSTK39 | |
| SCHEMBL8621586 | 0.89 | IL2 (0.54) | TLR8TLR7KDM4ENPC1ALDH1A1 | |
| SCHEMBL8662539 | 0.87 | GCGR (0.65) | GCGRPNLIPSTK39KDM4EMAPT | |
| SCHEMBL9324671 | 0.87 | TLR8 (0.57) | TLR8TLR7GCGRPNLIPSTK39 | |
| SCHEMBL8657705 | 0.86 | TLR8 (0.60) | TLR8TLR7KDM4ENPC1ALDH1A1 | |
| SCHEMBL10894702 | 0.85 | GCGR (0.62) | GCGRPNLIPSTK39MAPT | |
| SCHEMBL8662614 | 0.83 | TLR8 (0.47) | TLR8TLR7GCGRPNLIPSTK39 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776981-A | Use of acyl urea compounds for controlling endoparasites and ectoparasites of warm-blooded animals | NOVARTIS CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |
| US-5776982-A | Use of acyl urea compounds for controlling endoparasites and ectoparasites of warm-blooded animals | NOVARTIS CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |
| US-5420163-A | Insecticides or miticides | CIBA-GEIGY (US) | 1995-05-30 | — | — | US | disclosed |
| US-5135953-A | Oral or injections; cattle, swine, poultry | CIBA-GEIGY (US) | 1992-08-04 | — | — | US | disclosed |
| EP-0211004-A1 | USE OF ACYL UREA COMPOUNDS FOR CONTROLLING ENDOPARASITES AND ECTOPARASITES OF WARM-BLOODED ANIMALS | RHONE-POULENC NEDERLAND B.V. (NL) | 1987-02-25 | — | — | EP | disclosed |
| US-4602109-A | Novel pesticidal phenoxyphenyl and phenoxypyridyl benzoyl ureas and process for preparation | UNION CARBIDE CORPORATION (US) | 1986-07-22 | — | — | US | disclosed |
| WO-1986003941-A1 | USE OF ACYL UREA COMPOUNDS FOR CONTROLLING ENDOPARASITES AND ECTOPARASITES OF WARM-BLOODED ANIMALS | UNION CARBIDE CORPORATION (US) | 1986-07-17 | — | — | WO | disclosed |
| EP-0113247-B1 | PESTICIDAL PHENOXYPHENYL AND PHENOXYPYRIDYL BENZOYL UREAS AND PROCESS FOR THEIR PREPARATION | UNION CARBIDE CORPORATION (US) | 1986-06-11 | — | — | EP | disclosed |
| US-4540578-A | Pesticidal phenoxypyridyl benzoyl ureas | UNION CARBIDE CORPORATION (US) | 1985-09-10 | — | — | US | disclosed |
| EP-0113247-A1 | Pesticidal phenoxyphenyl and phenoxypyridyl benzoyl ureas and process for their preparation | UNION CARBIDE CORPORATION (US) | 1984-07-11 | — | — | EP | disclosed |