Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.64 |
| ▸ | NPC1 | O15118 | 4/20 | 0.64 |
| ▸ | RAB9A | P51151 | 4/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.64 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | CASP3 | P42574 | 2/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19396241 | 0.84 | SMN1; SMN2 (0.88) | SMN1; SMN2NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL11881427 | 0.84 | SMN1; SMN2 (0.88) | SMN1; SMN2NPC1RAB9AMAPTALDH1A1 | |
| Water SCHEMBL28061572 | 0.80 | NPC1 (0.96) | SMN1; SMN2NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL13437909 | 0.80 | SMN1; SMN2 (0.80) | SMN1; SMN2NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL11892894 | 0.80 | SMN1; SMN2 (0.80) | SMN1; SMN2NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL29352712 | 0.78 | NPC1 (1.00) | SMN1; SMN2NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL36840 | 0.78 | NPC1 (1.00) | SMN1; SMN2NPC1RAB9AMAPTALDH1A1 | |
| Anthraquinone SCHEMBL6310187 | 0.78 | NPC1 (1.00) | SMN1; SMN2NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL7148476 | 0.78 | MEN1 (0.43) | SMN1; SMN2NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL7318179 | 0.77 | NPC1 (0.96) | SMN1; SMN2NPC1RAB9AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5807837-A | ADMINISTERING TO TREAT HIV INFECTIONS TO INHIBIT THE REPLICATION OF FOREIGN NUCLEIC ACIDS IN A NORMAL CELL | SANKYO COMPANY, LIMITED (JP) | 1998-09-15 | — | — | US | disclosed |
| US-5674856-A | TREATMENT AND PROPHYLAXIS OF VIRAL INFECTIONS, INCLUDING AIDS AND TUMORS | SANKYO COMPANY, LIMITED (JP) | 1997-10-07 | — | — | US | disclosed |
| EP-0611075-B1 | Modified oligodeoxyribonucleotides, their preparation and their therapeutic use | SANKYO CO (JP) | 1996-12-18 | — | — | EP | disclosed |
| EP-0611075-A1 | Modified oligodeoxyribonucleotides, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1994-08-17 | — | — | EP | disclosed |