Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.40 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ACLY | P53396 | 3/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MCOLN2 | Q8IZK6 | 1/20 | 0.39 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.39 |
| ▸ | MCOLN1 | Q9GZU1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8661926 | 0.88 | HPGD (0.45) | KMT2AGAAHPGDL3MBTL1MAPT | |
| SCHEMBL8660175 | 0.88 | MAPT (0.53) | KMT2AHPGDL3MBTL1MAPTALDH1A1 | |
| SCHEMBL8662978 | 0.87 | HPGD (0.46) | KMT2AGAAHPGDMAPTALDH1A1 | |
| SCHEMBL8656218 | 0.87 | STAT3 (0.48) | KMT2AHPGDL3MBTL1MAPTALDH1A1 | |
| SCHEMBL8659710 | 0.86 | KIF11 (0.46) | KMT2AHPGDMAPTALDH1A1MEN1 | |
| SCHEMBL8662794 | 0.86 | HPGD (0.46) | KMT2AHPGDL3MBTL1MAPTALDH1A1 | |
| SCHEMBL8661649 | 0.85 | MEN1 (0.49) | KMT2AHPGDL3MBTL1MAPTALDH1A1 | |
| SCHEMBL8661718 | 0.85 | HPGD (0.46) | KMT2AGAAHPGDL3MBTL1MAPT | |
| SCHEMBL8659128 | 0.85 | HPGD (0.46) | KMT2AGAAHPGDMAPTALDH1A1 | |
| SCHEMBL8660150 | 0.85 | HPGD (0.47) | KMT2AGAAHPGDL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739166-A | ALKYLSULFONYL OR AMINOSULFONYL SUBSTITUTED AROMATIC COMPOUNDS AS NON-STEROIDAL ANTIINFLAMMATORY AGENT | G.D. SEARLE & CO. (US) | 1998-04-14 | — | — | US | disclosed |