Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | PDE5A | O76074 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8657989 | 0.91 | PDE5A (0.54) | ALDH1A1HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL8657996 | 0.91 | PDE5A (0.54) | ALDH1A1HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL8656450 | 0.89 | HTT (0.57) | ALDH1A1EPHX2HDAC1HDAC2HDAC3 | |
| SCHEMBL8656058 | 0.87 | HDAC1 (0.53) | ALDH1A1HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL8658543 | 0.84 | ALDH1A1 (0.58) | ALDH1A1HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL8656388 | 0.84 | ALDH1A1 (0.58) | ALDH1A1HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL8659610 | 0.84 | ALDH1A1 (0.58) | ALDH1A1HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL9402670 | 0.83 | PTPN11 (0.50) | ALDH1A1NPSR1LMNA | |
| SCHEMBL9362032 | 0.83 | HDAC1 (0.55) | ALDH1A1HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL8659682 | 0.82 | HDAC1 (0.54) | ALDH1A1HDAC1HDAC2HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5854250-A | N-benzoylamino acid derivatives, pharmaceutical compositions containing them and process of preparing same | GYOGYSZERKUTATO INTEZET KFT (HU) | 1998-12-29 | — | — | US | disclosed |
| US-5705529-A | ANTIISCHEMIC AGENTS, ANTIINFLAMMATORY AGENTS, AGING RESISTANCE, ATHERIOSCLEROSIS, NERVOUS SYSTEM DISORDERS | GYOGYSZERKUTATO INTEZET KFT (HK) | 1998-01-06 | — | — | US | disclosed |
| EP-0576941-B1 | N-benzoylamino acid derivatives, pharmaceutical compositions containing them and process for preparing same | NISSHIN FLOUR MILLING CO (JP) | 1997-09-03 | — | — | EP | disclosed |
| EP-0576941-A1 | N-benzoylamino acid derivatives, pharmaceutical compositions containing them and process for preparing same | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1994-01-05 | — | — | EP | disclosed |