Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL214170 | 0.89 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL5594093 | 0.89 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL3246522 | 0.86 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL3240027 | 0.86 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL5594492 | 0.85 | PTGS2 (0.76) | PTGS2PTGS1 | |
| SCHEMBL3242262 | 0.85 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL5594498 | 0.85 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL5594187 | 0.85 | PTGS2 (0.92) | PTGS2PTGS1 | |
| SCHEMBL3247213 | 0.85 | PTGS2 (0.92) | PTGS2PTGS1 | |
| SCHEMBL215573 | 0.85 | PTGS2 (1.00) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0859642-A2 | METHOD OF DETECTING CYCLOOXYGENASE-2 | G.D. SEARLE & CO. (US) | 1998-08-26 | — | — | EP | claimed |
| WO-1997014679-A2 | METHOD OF DETECTING CYCLOOXYGENASE-2 | G.D. SEARLE & CO. (US) | 1997-04-24 | — | — | WO | claimed |
| EP-0859642-A2 | METHOD OF DETECTING CYCLOOXYGENASE-2 | G.D. SEARLE & CO. (US) | 1998-08-26 | — | — | EP | disclosed |
| WO-1997014679-A2 | METHOD OF DETECTING CYCLOOXYGENASE-2 | G.D. SEARLE & CO. (US) | 1997-04-24 | — | — | WO | disclosed |