Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.68 |
| ▸ | PPARA | Q07869 | 5/20 | 0.51 |
| ▸ | PPARG | P37231 | 4/20 | 0.51 |
| ▸ | ACE | P12821 | 1/20 | 0.50 |
| ▸ | PPARD | Q03181 | 2/20 | 0.49 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 4/20 | 0.46 |
| ▸ | CTSK | P43235 | 3/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | MDM4 | O15151 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TDO2 | P48775 | 2/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8541445 | 0.84 | PPARA (0.60) | IDO1PPARAPPARGACEPPARD | |
| SCHEMBL12065748 | 0.84 | PPARA (0.60) | IDO1PPARAPPARGACEPPARD | |
| SCHEMBL24037243 | 0.84 | PPARA (0.60) | IDO1PPARAPPARGACEPPARD | |
| SCHEMBL30341699 | 0.84 | PPARA (0.60) | IDO1PPARAPPARGACEPPARD | |
| SCHEMBL29401813 | 0.83 | IDO1 (0.53) | IDO1PPARAPPARGACEMDM2 | |
| SCHEMBL8350968 | 0.83 | IDO1 (0.53) | IDO1PPARAPPARGACEMDM2 | |
| SCHEMBL7263706 | 0.83 | IDO1 (0.54) | IDO1PPARAPPARGACEMDM2 | |
| SCHEMBL999883 | 0.83 | MDM2 (0.52) | IDO1MDM2MDM4TP53 | |
| SCHEMBL3348411 | 0.83 | MDM2 (0.52) | IDO1MDM2MDM4TP53 | |
| SCHEMBL1000225 | 0.83 | MDM2 (0.52) | IDO1MDM2MDM4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871666-A1 | RECEPTOR-SELECTIVE SOMATOSTATIN ANALOGS | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1998-10-21 | — | — | EP | disclosed |
| US-5750499-A | ANTITUMOR | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1998-05-12 | — | — | US | disclosed |
| WO-1997014715-A1 | RECEPTOR-SELECTIVE SOMATOSTATIN ANALOGS | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1997-04-24 | — | — | WO | disclosed |