Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4A | O75164 | 1/20 | 0.65 |
| ▸ | ROR1 | Q01973 | 1/20 | 0.58 |
| ▸ | MC4R | P32245 | 9/20 | 0.57 |
| ▸ | MC5R | P33032 | 9/20 | 0.57 |
| ▸ | MC3R | P41968 | 9/20 | 0.57 |
| ▸ | MC1R | Q01726 | 9/20 | 0.57 |
| ▸ | TSLP | Q969D9 | 8/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8656601 | 0.90 | KDM4A (0.53) | KDM4AROR1MC4RMC5RMC3R | |
| SCHEMBL29924992 | 0.89 | MC4R (0.58) | KDM4AMC4RMC5RMC3RMC1R | |
| SCHEMBL29924705 | 0.87 | MC4R (0.57) | KDM4AMC4RMC5RMC3RMC1R | |
| SCHEMBL4602527 | 0.84 | TACR2 (0.65) | KDM4AMC4RMC5RMC3RMC1R | |
| SCHEMBL25941528 | 0.82 | PCSK9 (0.62) | KDM4ATSLP | |
| SCHEMBL8657322 | 0.81 | KDM4A (0.65) | KDM4AMC4RMC5RMC3RMC1R | |
| SCHEMBL25942530 | 0.80 | PCSK9 (0.61) | KDM4AROR1TSLP | |
| SCHEMBL14588779 | 0.80 | CXCR4 (0.51) | KDM4A | |
| SCHEMBL30538860 | 0.79 | TACR2 (0.56) | ROR1 | |
| SCHEMBL21429006 | 0.79 | TACR2 (0.56) | ROR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0741743-A1 | CYCLIC NEUROKININ A ANTAGONISTS | MERRELL PHARMACEUTICALS INC. (US) | 1996-11-13 | — | — | EP | claimed |
| WO-1995021187-A1 | CYCLIC NEUROKININ A ANTAGONISTS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1995-08-10 | — | — | WO | claimed |
| EP-0741743-B1 | CYCLIC NEUROKININ A ANTAGONISTS | MERRELL PHARMA INC (US) | 1998-10-14 | — | — | EP | disclosed |
| EP-0741743-A1 | CYCLIC NEUROKININ A ANTAGONISTS | MERRELL PHARMACEUTICALS INC. (US) | 1996-11-13 | — | — | EP | disclosed |
| US-5521156-A | HEXAPEPTIDES AND OCTAPEPTIDES | MERRELL PHARMACEUTICALS INC. (US) | 1996-05-28 | — | — | US | disclosed |
| WO-1995021187-A1 | CYCLIC NEUROKININ A ANTAGONISTS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1995-08-10 | — | — | WO | disclosed |