SCHEMBL29924705

SCHEMBL29924705

N=C(N)NCCC[C@@H]1NC(=O)CNC(=O)CNC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)CNC(=O)CNC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC1=O

nearest known ligand 0.57

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MC4R P32245 10/20 0.57
MC5R P33032 10/20 0.57
MC3R P41968 10/20 0.57
MC1R Q01726 10/20 0.57
KDM4A O75164 1/20 0.55
TACR2 P21452 5/20 0.49
TSLP Q969D9 4/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29924992 0.98 MC4R (0.58) MC4RMC5RMC3RMC1RKDM4A
SCHEMBL8659758 0.87 KDM4A (0.65) MC4RMC5RMC3RMC1RKDM4A
SCHEMBL23317973 0.85 OPRM1 (0.58) MC4RMC5RMC3RMC1RKDM4A
SCHEMBL23318156 0.85 OPRM1 (0.64) MC4RMC5RMC3RMC1RKDM4A
SCHEMBL29925129 0.84 HDAC8 (0.49) MC4RMC5RMC3RMC1RKDM4A
SCHEMBL19831554 0.84 OPRM1 (0.61) MC4RMC5RMC3RMC1RKDM4A
SCHEMBL16488478 0.83 ITGB3 (0.61) MC4RMC5RMC3RMC1RTSLP
SCHEMBL22215871 0.82 MC4R (0.52) MC4RMC5RMC3RMC1RKDM4A
SCHEMBL27423920 0.82 MC4R (0.48) MC4RMC5RMC3RMC1R
SCHEMBL8207851 0.82 MC4R (0.48) MC4RMC5RMC3RMC1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220289794-A1 SYNTHETIC ANTIMICROBIAL PEPTIDES AJK BIOPHARMACEUTICAL LLC (US) 2022-09-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220289794-A1 SYNTHETIC ANTIMICROBIAL PEPTIDES VIP, HM13, NGLY1 MC4R 1798/4885MC5R 3698/4885MC3R 2519/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.