Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 13/20 | 0.67 |
| ▸ | PDE4B | Q07343 | 13/20 | 0.67 |
| ▸ | PDE4C | Q08493 | 13/20 | 0.67 |
| ▸ | PDE4D | Q08499 | 13/20 | 0.67 |
| ▸ | ADORA2A | P29274 | 11/20 | 0.67 |
| ▸ | ADORA2B | P29275 | 10/20 | 0.57 |
| ▸ | CHIT1 | Q13231 | 1/20 | 0.54 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
| ▸ | CFTR | P13569 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butane SCHEMBL8658759 | 0.99 | PDE4A (0.65) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| Butane SCHEMBL8660047 | 0.97 | PDE4A (0.68) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| Ammonia Solution, Strong SCHEMBL8660123 | 0.96 | PDE4A (0.62) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| Ammonia Solution, Strong SCHEMBL8660128 | 0.96 | PDE4A (0.62) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| Butane SCHEMBL8655301 | 0.90 | ADORA2B (0.67) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL21381258 | 0.82 | PDE4A (0.92) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL7458212 | 0.81 | PDE4A (0.89) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL7109948 | 0.81 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL8656750 | 0.80 | PDE4A (0.87) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| Butane SCHEMBL8657379 | 0.79 | TNF (0.60) | PDE4APDE4BPDE4CPDE4DADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5728686-A | TREATMENT OF MUSCULAR DYSTROPHY | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-03-17 | — | — | US | disclosed |