Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 7/20 | 0.53 |
| ▸ | PDE4A | P27815 | 4/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.53 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.53 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.53 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | TNF | P01375 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8656403 | 0.96 | ADORA2B (0.55) | ADORA2BPDE4AADORA2APDE4BPDE4C | |
| SCHEMBL8660068 | 0.95 | ADORA2B (0.54) | ADORA2BPDE4AADORA2APDE4BPDE4C | |
| SCHEMBL8660222 | 0.93 | ADORA2B (0.56) | ADORA2BPDE4AADORA2APDE4BPDE4C | |
| SCHEMBL8656830 | 0.92 | PDE4A (0.48) | ADORA2BPDE4AADORA2APDE4BPDE4C | |
| SCHEMBL8656053 | 0.91 | PDE4A (0.53) | ADORA2BPDE4AADORA2APDE4BPDE4C | |
| SCHEMBL8656410 | 0.91 | PDE4A (0.61) | ADORA2BPDE4AADORA2APDE4BPDE4C | |
| SCHEMBL8660013 | 0.90 | PDE4A (0.60) | ADORA2BPDE4AADORA2APDE4BPDE4C | |
| SCHEMBL8660178 | 0.90 | PDE4A (0.51) | ADORA2BPDE4AADORA2APDE4BPDE4C | |
| SCHEMBL7465081 | 0.90 | ADORA2B (0.55) | ADORA2BPDE4AADORA2APDE4BPDE4C | |
| SCHEMBL8657417 | 0.89 | PDE4A (0.47) | ADORA2BPDE4AADORA2APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5728686-A | TREATMENT OF MUSCULAR DYSTROPHY | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-03-17 | — | — | US | disclosed |