Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | ACLY | P53396 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.42 |
| ▸ | NAT1 | P18440 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8662810 | 0.90 | HPGD (0.51) | HPGDERBB2HSP90AA1HSP90AB1MAPT | |
| SCHEMBL8658312 | 0.90 | HPGD (0.53) | HPGDERBB2HSP90AA1HSP90AB1MAPT | |
| SCHEMBL8661239 | 0.89 | HPGD (0.52) | HPGDERBB2HSP90AA1HSP90AB1MAPT | |
| SCHEMBL8659966 | 0.88 | HPGD (0.59) | HPGDMAPTPOLBALDH1A1GAA | |
| SCHEMBL8656156 | 0.87 | HPGD (0.50) | HPGDERBB2HSP90AA1HSP90AB1MAPT | |
| SCHEMBL8660883 | 0.87 | HPGD (0.50) | HPGDMAPTPOLBKDM4EALDH1A1 | |
| SCHEMBL8662984 | 0.87 | HPGD (0.50) | HPGDERBB2HSP90AA1HSP90AB1MAPT | |
| SCHEMBL8661048 | 0.87 | HPGD (0.50) | HPGDMAPTPOLBKDM4EALDH1A1 | |
| SCHEMBL8658003 | 0.85 | HPGD (0.51) | HPGDMAPTPOLBKDM4EALDH1A1 | |
| SCHEMBL8661509 | 0.85 | HPGD (0.53) | HPGDMAPTPOLBKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739166-A | ALKYLSULFONYL OR AMINOSULFONYL SUBSTITUTED AROMATIC COMPOUNDS AS NON-STEROIDAL ANTIINFLAMMATORY AGENT | G.D. SEARLE & CO. (US) | 1998-04-14 | — | — | US | disclosed |