Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | FASN | P49327 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7306710 | 0.84 | EPHX1 (0.54) | EPHX1SLC6A2SLC6A4SLC6A3TAAR1 | |
| Hydrochloric Acid SCHEMBL7301303 | 0.82 | EPHX1 (0.52) | EPHX1SLC6A2SLC6A4SLC6A3TAAR1 | |
| SCHEMBL11687983 | 0.73 | FASN (0.53) | SLC6A2SLC6A4SLC6A3FASNTAAR1 | |
| Hydrochloric Acid SCHEMBL7295838 | 0.72 | MAOB (0.44) | MAOASIGMAR1ANPEP | |
| SCHEMBL5172288 | 0.72 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3FASNTAAR1 | |
| SCHEMBL5864654 | 0.72 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3FASNTAAR1 | |
| SCHEMBL8200189 | 0.72 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3FASNTAAR1 | |
| SCHEMBL8786930 | 0.72 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3FASNTAAR1 | |
| Hydrochloric Acid SCHEMBL7303614 | 0.72 | ANPEP (0.44) | EPHX1SLC6A2SLC6A4SLC6A3TAAR1 | |
| SCHEMBL5973222 | 0.69 | TDP1 (0.46) | SLC6A2SLC6A4SLC6A3FASN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763631-A | CIS-EPOXIDE COMPOUNDS; ANTIVIRUS AGENTS; USEFUL TO TREAT THE AIDS | LUCKY LIMITED (KR) | 1998-06-09 | — | — | US | disclosed |
| US-5744621-A | CIS-EPOXIDE COMPOUNDS | LUCKY LIMITED. (KR) | 1998-04-28 | — | — | US | disclosed |
| US-5587388-A | AIDS; VIRICIDES | LUCKY LIMITED (KR) | 1996-12-24 | — | — | US | disclosed |
| EP-0601486-A1 | Cis-epoxide derivatives useful as irreversible HIV protease inhibitors and process and intermediates for their preparation | LUCKY LTD. (KR) | 1994-06-15 | — | — | EP | disclosed |