SCHEMBL8660397

SCHEMBL8660397

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nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12281776 0.90 TSHR (0.37) TSHR
SCHEMBL22506801 0.87 LMNA (0.40) TSHR
SCHEMBL22535981 0.87 LMNA (0.40) TSHR
SCHEMBL15821730 0.84 MPI (0.34) TSHR
SCHEMBL17390324 0.79 TSHR (0.37) TSHR
SCHEMBL4278701 0.75
SCHEMBL9615262 0.75
SCHEMBL4592237 0.73
SCHEMBL13405339 0.71
SCHEMBL12958005 0.70 TSHR (0.34) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017192407-A1 MICROCAPSULES FOR CONTROLLED DELIVERY OF AN ACTIVE PHARMACEUTICAL INGREDIENT BIELSKI ROMAN (US) 2017-11-09 WO disclosed
US-5830920-A PREVENTION GROWTH OF SMOOTH MUSCLE CELLS HOFFMANN-LA ROCHE INC. (US) 1998-11-03 US disclosed