O-Xylene

O-Xylene

SCHEMBL8660595

Cc1ccccc1C.Cc1ccccc1S(=O)(=O)O

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MYC P01106 1/20 0.52
TSHR P16473 2/20 0.48
ACHE P22303 1/20 0.48
RAPGEF4 Q8WZA2 1/20 0.44
SUMO2 P61956 1/20 0.42
SUMO1 P63165 1/20 0.42
SENP7 Q9BQF6 1/20 0.42
SENP3 Q9H4L4 1/20 0.42
SENP2 Q9HC62 1/20 0.42
SENP1 Q9P0U3 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
HSD11B1 P28845 1/20 0.42
KMT2A Q03164 3/20 0.41
MEN1 O00255 2/20 0.41
ESR1 P03372 2/20 0.41
ESR2 Q92731 2/20 0.41
GAA P10253 1/20 0.41
SLC1A3 P43003 1/20 0.41
SLC1A2 P43004 1/20 0.41
SLC1A1 P43005 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1748 0.98 MYC (0.53) MYCTSHRACHERAPGEF4SUMO2
SCHEMBL29392580 0.98 MYC (0.53) MYCTSHRACHERAPGEF4SUMO2
Ammonia Solution, Strong SCHEMBL6360239 0.95 MYC (0.52) MYCTSHRACHERAPGEF4SUMO2
Water SCHEMBL8126703 0.95 MYC (0.52) MYCTSHRACHERAPGEF4SUMO2
Water SCHEMBL3917281 0.95 MYC (0.52) MYCTSHRACHERAPGEF4SUMO2
SCHEMBL6916771 0.95 MYC (0.52) MYCTSHRACHERAPGEF4SUMO2
SCHEMBL2045309 0.95 MYC (0.52) MYCTSHRACHERAPGEF4SUMO2
SCHEMBL8715920 0.95 MYC (0.52) MYCTSHRACHERAPGEF4SUMO2
Lithium SCHEMBL11112963 0.95 MYC (0.52) MYCTSHRACHERAPGEF4SUMO2
SCHEMBL948871 0.95 MYC (0.52) MYCTSHRACHERAPGEF4SUMO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0242620-B1 MODIFIED PHENOLIC FOAM CATALYSTS AND METHOD FIBERGLAS CANADA Inc. (CA) 1991-06-12 EP claimed
US-4945077-A Aromatic sulfonic acid and resorcinol FIBERGLASS CANADA INC. (CA) 1990-07-31 US claimed
US-4883824-A AROMATIC SULFONIC ACID AND DIHYDRIC PHENOL TO PRODUCE CLOSED CELL FOAM FIBERGLAS CANADA, INC. (CA) 1989-11-28 US claimed
US-5786398-A PHENOL-FORMALDEHYDE RESINS; THERMOCONDUCTIVITY OWENS-CORNING FIBERGLAS TECHNOLOGY INC. (US) 1998-07-28 US disclosed
CN-1179167-A Insulating foam plastic and its manufacturing method OWENS CORNING CO (US) 1998-04-15 CN disclosed
EP-0815163-A1 INSULATING FOAMS AND THE MANUFACTURING THEREOF OWENS CORNING (US) 1998-01-07 EP disclosed
WO-1996030437-A1 INSULATING FOAMS AND THE MANUFACTURING THEREOF OWENS CORNING (US) 1996-10-03 WO disclosed
EP-0242620-B1 MODIFIED PHENOLIC FOAM CATALYSTS AND METHOD FIBERGLAS CANADA Inc. (CA) 1991-06-12 EP disclosed
US-4945077-A Aromatic sulfonic acid and resorcinol FIBERGLASS CANADA INC. (CA) 1990-07-31 US disclosed
US-4883824-A AROMATIC SULFONIC ACID AND DIHYDRIC PHENOL TO PRODUCE CLOSED CELL FOAM FIBERGLAS CANADA, INC. (CA) 1989-11-28 US disclosed
EP-0242620-A2 Modified phenolic foam catalysts and method FIBERGLAS CANADA Inc. (CA) 1987-10-28 EP disclosed
EP-0218608-A4 LOW-FOAMING COMPOSITIONS. GLUCK BRUNO A 1987-07-09 EP disclosed
EP-0218608-A1 LOW-FOAMING COMPOSITIONS. GLUCK BRUNO A 1987-04-22 EP disclosed
WO-1986005510-A1 LOW-FOAMING COMPOSITIONS GLUCK BRUNO A 1986-09-25 WO disclosed