Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.52 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.44 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.42 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP3 | Q9H4L4 | 1/20 | 0.42 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.42 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL59880 | 1.00 | MYC (0.52) | MYCRAPGEF4SUMO2SUMO1SENP7 | |
| Ammonia Solution, Strong SCHEMBL28265117 | 0.98 | MYC (0.50) | MYCRAPGEF4SUMO2SUMO1SENP7 | |
| Hydrochloric Acid SCHEMBL11128060 | 0.98 | MYC (0.50) | MYCRAPGEF4SUMO2SUMO1SENP7 | |
| SCHEMBL1748 | 0.98 | MYC (0.53) | MYCRAPGEF4SUMO2SUMO1SENP7 | |
| SCHEMBL29392580 | 0.98 | MYC (0.53) | MYCRAPGEF4SUMO2SUMO1SENP7 | |
| SCHEMBL948871 | 0.95 | MYC (0.52) | MYCRAPGEF4SUMO2SUMO1SENP7 | |
| Lithium SCHEMBL11112963 | 0.95 | MYC (0.52) | MYCRAPGEF4SUMO2SUMO1SENP7 | |
| Water SCHEMBL8126703 | 0.95 | MYC (0.52) | MYCRAPGEF4SUMO2SUMO1SENP7 | |
| SCHEMBL6916771 | 0.95 | MYC (0.52) | MYCRAPGEF4SUMO2SUMO1SENP7 | |
| Water SCHEMBL3917281 | 0.95 | MYC (0.52) | MYCRAPGEF4SUMO2SUMO1SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050026966-A1 | Process and chiral amine intermediates useful for preparation of antiproliferative 2,4-diaminothiazole amide compounds | AGOURON PHARMACEUTICALS, INC. | 2005-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050026966-A1 | Process and chiral amine intermediates useful for preparation of antiproliferative 2,4-diaminothiazole amide compounds | DDC, TK1, AADAT | MYC 402/4885RAPGEF4 3187/4885SUMO2 2354/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.