SCHEMBL8660665

SCHEMBL8660665

C=COC(CCCCC)N(CCC)CCC

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PLA2G1B P04054 1/20 0.32
PLA2G2A P14555 1/20 0.32
OPRM1 P35372 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8660266 0.94 TSHR (0.31) TSHR
SCHEMBL8664143 0.93 PLA2G1B (0.32) PLA2G1BPLA2G2AOPRM1TSHR
SCHEMBL8660251 0.87 PLA2G1B (0.32) PLA2G1BPLA2G2AOPRM1TSHR
SCHEMBL8665071 0.86
SCHEMBL8663425 0.85 PLA2G1B (0.35) PLA2G1BPLA2G2AOPRM1TSHR
SCHEMBL8665331 0.83
SCHEMBL8663268 0.81 TSHR (0.32) TSHR
SCHEMBL8663604 0.81 TSHR (0.32) OPRM1TSHR
SCHEMBL8662944 0.80 FDPS (0.30)
SCHEMBL8661836 0.79 TSHR (0.35) PLA2G1BPLA2G2AOPRM1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0458479-B1 Pigment dispersing agent NIPPON OILS & FATS CO LTD (JP) 1998-11-25 EP disclosed
US-5244979-A Paints NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1993-09-14 US disclosed
EP-0458479-A2 Pigment dispersing agent NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1991-11-27 EP disclosed