SCHEMBL8660745

SCHEMBL8660745

CCCCCCCC/C=C\CCCCCCCCOP(O)(=S)OC(C)CC

nearest known ligand 0.63

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LPAR3 Q9UBY5 13/20 0.63
LPAR2 Q9HBW0 10/20 0.63
LPAR1 Q92633 6/20 0.63
P2RY10 O00398 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8469597 0.91 LPAR3 (0.56) LPAR3LPAR2LPAR1
SCHEMBL8468251 0.85 LPAR3 (0.80) LPAR3LPAR2LPAR1
SCHEMBL13355654 0.79 LPAR3 (0.71) LPAR3LPAR2LPAR1P2RY10
SCHEMBL13355657 0.79 LPAR3 (0.71) LPAR3LPAR2LPAR1P2RY10
SCHEMBL192973 0.78 LPAR3 (1.00) LPAR3LPAR2LPAR1
SCHEMBL10017367 0.78 LPAR3 (1.00) LPAR3LPAR2LPAR1
SCHEMBL3832990 0.78 LPAR3 (1.00) LPAR3LPAR2LPAR1
SCHEMBL11876469 0.78 LPAR3 (0.60) LPAR3LPAR2LPAR1
SCHEMBL10017369 0.78 LPAR3 (1.00) LPAR3LPAR2LPAR1
SCHEMBL8661135 0.78 LPAR3 (0.60) LPAR3LPAR2LPAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0531585-B1 Oil additive concentrates and lubricants of enhanced performance capabilities ETHYL PETROLEUM ADDITIVES LTD (GB) 1998-11-04 EP disclosed
US-5464549-A Oil soluble dispersants suitable for use in fuels and lubricants ETHYL CORPORATION (US) 1995-11-07 US disclosed
US-5358652-A Using 3,5-dihydrocarbyl-4-hydroxybenzylamine compound ETHYL PETROLEUM ADDITIVES, LIMITED (GB) 1994-10-25 US disclosed
US-5241003-A Post-treated polyisobutenyl succinimide; crankcase, transmission oils ETHYL PETROLEUM ADDITIVES, INC. (US) 1993-08-31 US disclosed
EP-0531585-A1 Oil additive concentrates and lubricants of enhanced performance capabilities ETHYL PETROLEUM ADDITIVES LIMITED (GB) 1993-03-17 EP disclosed
US-5137980-A Reacting polyisobutene with aacidic reactant; super atmospheric pressure; low tar rating ETHYL PETROLEUM ADDITIVES, INC. (US) 1992-08-11 US disclosed